Download Computer-Aided Design of Microfluidic Very Large Scale by Kai Hu, Krishnendu Chakrabarty, Tsung-Yi Ho PDF

By Kai Hu, Krishnendu Chakrabarty, Tsung-Yi Ho

This e-book presents a finished assessment of flow-based, microfluidic VLSI. The authors describe and resolve in a accomplished and holistic demeanour functional demanding situations similar to regulate synthesis, wash optimization, layout for testability, and analysis of recent flow-based microfluidic biochips. They introduce useful options, according to rigorous optimization and formal types. The technical contributions offered during this booklet won't in simple terms shorten the product improvement cycle, but additionally speed up the adoption and extra improvement of recent flow-based microfluidic biochips, by means of facilitating the whole exploitation of layout complexities which are attainable with present fabrication techniques.

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Additional info for Computer-Aided Design of Microfluidic Very Large Scale Integration (mVLSI) Biochips

Sample text

To reduce the number of control pins without losing much-needed functionality or operational flexibility, we propose an operation-based compatibility identification method that relies on the compatibilities between valves based on component actions, instead of a pre-determined and complete control-logic table. To increase the likelihood of success in routing, two incremental control-layer design methods are presented. These approaches take a global view of the impact of routability at each design stage by incrementally increasing the routing priorities of failed routing attempts.

This procedure is repeated until all valves are connected to the control pins or an unroutable decision is made. 2. The baseline method cannot find feasible routing solutions for Benchmarks 2, 5, and 6; however, Algorithm 1 successfully addresses all test cases. Moreover, Algorithm 1 also achieves a 15% reduction in the number of pumps, a 36% reduction in total channel length, a 76% reduction in skew, and a 33% reduction in latency on average for the completed test cases (Benchmarks 1, 3, and 4).

Mix, dilution, detection). A number of fluidic components, as basic functional modules, are bound to these operations and placed in the flow layer. The execution of a standard component can be divided into several control actions. Thus, instead of the establishment of a complete pre-determined control-logic table, we identify compatibility based on the control actions of each component to avoid loss of functionality. For example, to execute the mix operation in a mixer, whose layout is shown in Fig.

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