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By U. Boas, J. B. Christensen, P. M. H. Heegaard

Книга Dendrimers in medication and Biotechnology: New Molecular instruments Dendrimers in medication and Biotechnology: New Molecular ToolsКниги Медицина Автор: U. Boas, J.B. Christensen, P.M.H. Heegaard Год издания: 2006 Формат: pdf Издат.:Royal Society of Chemistry Страниц: 182 Размер: 5,1 ISBN: 0854048529 Язык: Английский0 (голосов: zero) Оценка:Dendrimers are a brand new type of macromolecule more and more utilized in the fields of man-made natural chemistry, biology, drugs and biotechnology. Dendrimers in medication and Biotechnology: New Molecular instruments appears at this interesting and quickly becoming sector of technology. utilizing an interdisciplinary technique with specific emphasis on organic purposes, the ebook discusses the connection among the dendrimer molecular motif and its organic properties.A common creation to the topic of dendrimers, together with definitions of phrases and emblems, is supplied. next sections talk about issues together with dendrimers in organic structures, dendrimers as drug supply units, dendrimers in diagnostics and dendrimer medicinal drugs. during the ebook, examples from present learn also are provided.This ebook will entice a variety of scientists, together with non-specialists who require an creation to dendrimers, in addition to these wishing to grasp extra concerning the purposes of dendrimers within the fields of biology and medication.

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1). The decreased entropy loss of binding the second ligand arm makes this a highly favourable reaction from a thermodynamic point of view, thus shifting the equilibrium strongly towards binding of this second ligand site. The phenomenon of binding-affinities being much larger in multivalent interactions than the expected additive affinity increase based on the system valency, has been given different terms depending on the scientific context encountering and treating this effect. In inorganic coordination chemistry, the strong interaction between multivalent (or multidentate) ligands with metal ions is denoted “the chelate effect” where the most widely used ligand based on this property may be the very well-known hexavalent ligand “EDTA” used for vast amount of applications due to its strong complexation to divalent earth metals.

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